About IncDNA-BF

Amphioxus (Branchiostoma floridae) is a promising animal model in evolutionary understanding of organ development from a view of invertebrate-vertebrate transition. Unfortunately, current Amphioxus genomes are not good enough to support reliable -omics research, in particular, help assemble high quality transcriptome. Therefore, we constructed an integrative cDNA library from heterogenous RNA-seq datasets and EST data. Transcriptome assembled by referring to this library show superior to that by genome-based or de novo methods. In summary, the integrative cDNA library can be a practical solution in replace of genome for large scale -omics studies. It will be particularly useful for systematic and dynamic exploration of gene behavior, regardless of the genome quality.

Adult Amphioxus (Branchiostoma floridae) Supplied by YiQuan Wang and Guang Li, Developmental Genetics and Comparative Genomics Group, State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University. All right reserved.